Ankylosing Spondylitis: Understanding, Diagnosis and Treatment Options
March 25, 2025

Ankylosing spondylitis is a chronic inflammatory condition that primarily affects the spine, causing pain, stiffness, and potential fusion of the vertebrae. This challenging condition impacts thousands of Australians, with a notable 3:1 ratio of males to females being diagnosed. Though it presents significant challenges, proper ankylosing spondylitis treatment can allow those affected to manage their symptoms effectively and maintain their quality of life.
What is Ankylosing Spondylitis?
Ankylosing spondylitis (AS) belongs to a group of conditions known as spondyloarthritis. It is a progressive inflammatory disease that primarily affects the spine, particularly the sacroiliac joints where the spine connects to the pelvis. Over time, chronic inflammation can lead to the formation of new bone, potentially causing sections of the spine to fuse together, reducing flexibility and resulting in a hunched-forward posture in advanced cases.
Whilst the spine is the main focus of the condition, ankylosing spondylitis may also affect other joints in some cases. Additionally, some patients experience inflammation in other parts of the body, including the eyes, heart, lungs, and kidneys, though these extra-articular manifestations are less common.
Ankylosing Spondylitis Causes and Risk Factors
Understanding the underlying ankylosing spondylitis causes helps both patients and practitioners develop effective management strategies. Whilst the exact cause remains not fully understood, several factors contribute to its development:
Genetic Factors
Genetics play a significant role in ankylosing spondylitis. The HLA-B27 gene is present in approximately 90% of people with AS, though merely having this gene doesn't guarantee developing the condition. Many people with HLA-B27 never develop ankylosing spondylitis, indicating that additional factors must be involved.
Environmental Triggers
Research suggests that environmental factors may trigger the onset of AS in genetically susceptible individuals. These triggers might include:
* Bacterial infections, particularly in the gastrointestinal tract
* Mechanical stress on the spine
* Hormonal factors (which may partly explain the male predominance)
Autoimmune Connection
Ankylosing spondylitis reason may also be linked to autoimmune mechanisms, where the body's immune system mistakenly attacks healthy tissues. This inappropriate immune response leads to inflammation in the entheses (where ligaments and tendons attach to bones), a hallmark feature of AS.
Age and Gender
AS typically begins in late adolescence or early adulthood, with most patients diagnosed between 15 and 45 years of age. The condition affects men three times more frequently than women, though female ankylosing spondylitis experiences are increasingly recognised as potentially distinct in presentation.
Recognising Ankylosing Spondylitis Symptoms
Early recognition of ankylosing spondylitis symptoms is crucial for prompt diagnosis and treatment. The condition typically develops gradually, with symptoms often subtle at first but progressively worsening over time.
The most common ankylosing spondylitis symptoms include:
* Low back pain and stiffness, typically worse in the morning or after periods of inactivity
* Pain that improves with physical activity
* Pain that may wake you during the night, particularly in the second half of the night
* Buttock pain that may alternate from one side to the other
* Fatigue and reduced energy levels
* Limited expansion of the chest due to involvement of the joints between the ribs and spine
As the condition progresses, additional symptoms may develop:
* Reduced spinal mobility and difficulty with daily activities
* Postural changes, including stooped shoulders and a forward-leaning posture
* Pain and stiffness in other joints such as shoulders, hips, knees, or ankles
* Inflammation of the eyes (uveitis), causing pain, redness, and sensitivity to light
* In rare cases, involvement of the heart or lungs
Female ankylosing spondylitis chiropractors have noted that women may experience the condition differently than men. Women with AS tend to have:
* More neck, peripheral joint, and widespread pain
* Less radiographic evidence of spinal changes
* More frequent disease flares
* Different patterns of progression
Comprehensive Ankylosing Spondylitis Treatment Approaches
Whilst there is no cure for ankylosing spondylitis, effective treatment can reduce pain, maintain mobility, and prevent or delay complications. A multimodal approach typically yields the best results.
Many patients with ankylosing spondylitis find significant relief through chiropractic approaches:
* Gentle mobilisation techniques for stiff joints
* Advanced BioStructural Correction to address postural changes
* Soft tissue therapies to reduce muscle tension
* Education on self-management strategies
Importantly, these approaches should be tailored to the individual's specific presentation and stage of disease, with modifications as necessary to ensure safety and effectiveness.
Several lifestyle changes can support overall management:
* Maintaining good posture during daily activities
* Using appropriate ergonomic equipment at work and home
* Applying heat or cold therapy as needed for symptom relief
* Quitting smoking, which is associated with worse outcomes in AS
* Managing stress through mindfulness, meditation, or other techniques
Living Successfully with Ankylosing Spondylitis
Despite the challenges it presents, many people with ankylosing spondylitis lead active, fulfilling lives. Australian cricketer Michael Slater serves as an inspiring example, managing his condition whilst becoming one of Australia's greatest batsmen. With proper treatment and self-management, most patients can continue their life plans and maintain good quality of life.
Key strategies for successful living with AS include:
* Adhering to treatment plans and regular monitoring
* Staying physically active even during mild flares
* Building a support network of healthcare providers, family, and friends
* Joining support groups to connect with others who understand the condition
* Setting realistic goals and celebrating achievements
Ankylosing Spondylitis Treatment - The Role of Personalised Care
Working with healthcare providers experienced in ankylosing spondylitis is essential for optimal management. For female patients, seeking female ankylosing spondylitis specialists may provide additional insights into gender-specific aspects of the condition.
At our clinic, we offer personalised care for people with ankylosing spondylitis, including advanced BioStructural correction techniques that may assist in managing pain and stiffness. Our approach focuses on maintaining spinal mobility, improving posture, and enhancing overall function to help you maintain the quality of life you deserve.
If you're experiencing symptoms of ankylosing spondylitis or have already been diagnosed and are seeking additional support for managing your condition, we invite you to contact our team. Let us help you explore how our techniques may benefit your specific situation and complement your existing treatment plan.
Living with ankylosing spondylitis doesn't mean giving up the activities and lifestyle you enjoy. With proper care, support, and self-management strategies, you can effectively manage this condition and continue pursuing your goals and passions.
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